Capcom's biggest showing at E3 is the upcoming Lost Planet 2.  The game appeared in playable form at the recent E3 conference, pitting up to 4 players co-operatively against a gigantic 6-legged boss, called an Akrid.  In a very grandiose Shadow of the Colossus-like experience, players must target weak spots on the boss in order to bring it down.

At E3, Capcom confirmed that a demo of Lost Planet 2 will be launched, for at least the PS3.  The timeline for the demo and the retail release  hasn't been established as of yet, nor was it clarified if the demo at E3 will be the one released.  Capcom had previously confirmed a demo for the 360 and PC, before the PS3 platform was announced. 

Lost Planet 2 is a third person shooter, developed internally by Capcom.  It's been penciled in for a 2009 release, for the PS3, PC and XBox 360.